Search on: SEX HORMONE-BINDING GLOBULIN 
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Descriptor English:   Sex Hormone-Binding Globulin 
Descriptor Spanish:   Globulina de Unión a Hormona Sexual 
Descriptor Portuguese:   Globulina de Ligação a Hormônio Sexual 
Synonyms English:   Binding Globulin, Testosterone-Estradiol
Globulin, Sex Hormone-Binding
Globulin, Testosterone-Estradiol Binding
Hormone-Binding Globulin, Sex
Sex Hormone Binding Globulin
Sex Steroid Binding Protein
Steroid-Binding Protein, Sex
Testosterone Estradiol Binding Globulin
Testosterone-Estradiol Binding Globulin
Sex Steroid-Binding Protein  
Tree Number:   D12.776.124.790.223.800
D12.776.157.762
D12.776.377.715.182.800
Definition English:   A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Sex hormone-binding protein has the same amino acid sequence as ANDROGEN-BINDING PROTEIN. They differ by their sites of synthesis and post-translational oligosaccharide modifications. 
Indexing Annotation English:   does not refer to all sex hormones: refers to a specific protein in the blood binding only testosterone or estradiol; for other sex hormone-binding globulins consider ANDROGEN-BINDING PROTEIN & PROGESTERONE-BINDING GLOBULIN; DF: SHBG
See Related English:   Androgen-Binding Protein
 
History Note English:   77; SEX STEROID-BINDING PROTEIN was SEX-STEROID-BINDING PROTEIN (NM) 1981-91; ESTRADIOL-BINDING GLOBULIN & TESTOSTERONE-BINDING GLOBULIN were see SEX HORMONE-BINDING GLOBULIN 1977-92 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   22292 
Unique Identifier:   D012738 

Occurrence in VHL:
 

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